What is the best duration for nicotine replacement therapy?

• —525 smokers enrolled.
• —Randomized groups for nicotine replacement via patch at 8, 24, 52 weeks
• —6 month cessation rates were significantly higher if patches used for 24 wks. vs 8 wks.
• —No adverse effects noted
• —Cost effective benefit long term.
• —No additional therapeutic advantage with long term treatment (up to 52 weeks)
• —Worsened adherence after 24 weeks
• —Likely difficulties adhering to patch treatment for such a long period of time.

A.

• 24 week duration of treatment is best.
• —Suggested use of Champix (varencicline tartrate) or combination nicotine replacement therapy for better results.